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The latest Mainline newsletters for the General Public are listed here.


For healthcare professionals we have a Mainline newsletter in a Professional version here.


What will 1 out of every three seniors experience this year? A Fall! Why?

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Volume 2 August 9, 2005 Number 4

An Exclusive Continuing Education Publication of Acadiana Consultant Pharmacy Service
Author, Publisher, Editor-in Chief, Typesetter & Printer, Charles S. Feucht,PD,FASCP PharmD candidate

Medication News & Update

The drugs Actos and Avandia are use to treat elevated sugar levels in diabetic patients. This is their primary reason for use and benefits to diabetic patients. However,  a recent study has shown that they also provide additional benefits to patients with respect to cholesterol levels.  Both of these drugs belong to a class know as thiazolidinediones also called "glitazones" for short. or TZDs.  Both of the drugs have equal effects of lowering blood sugars but there is a difference in their ability to benefit the patient with respect to cholesterol levels. Pioglitazone (Actos) improves lipids better than rosiglitazone (Avandia). Pioglitazone(Actos) seems  to be better at lowering triglycerides and increasing HDL(good cholesterol). Pioglitazone LOWERS triglycerides about 9% to 12%... whereas rosiglitazone can INCREASE triglycerides up to 15%.
      Pioglitazone also raises HDL about 12% to 19%...compared to 8% to 19% for rosiglitazone.



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